20. Sam Bradford – 1st overall to Rams in 2010:
Heisman-winning quarterback Sam Bradford has some of the best success in terms of pure football performance on this list. In fact, he was the Offensive Rookie of the Year in 2010. However, it’s his injury history, draft position, and sheer cost that make him a huge bust at the end of the day. Often injured at Oklahoma, that continued into his NFL career in a big way.
After playing only seven combined games from 2013-2014, Bradford was traded to Philadelphia. He started 14 games and played well enough to command a first and fourth-round pick from the Vikings when their starting QB Teddy Bridgewater went down the following year. Despite solid enough numbers, he never led Minnesota to the playoffs and was injured the following year. Before the 2018 season, Bradford signed what looks like one of the worst contracts in NFL history with a potential $20 million, two-year deal with Arizona. After three horrific starts, he flamed out of the NFL. True, he wasn’t terrible, but elite players such as Ndamukong Suh, Gerald McCoy, Trent Williams, Eric Berry, Russell Okung, Joe Haden, and Earl Thomas were all selected after him in the 2010 draft.